mrspoonsi (2955715) writes A project aiming to revolutionise medicine by unlocking the secrets of DNA is under way in centres across England. Prime Minister David Cameron has said it "will see the UK lead the world in genetic research within years". The first genetic codes of people with cancer or rare diseases, out of a target of 100,000, have been sequenced. Experts believe it will lead to targeted therapies and could make chemotherapy "a thing of the past". Just one human genome contains more than three billion base pairs — the building blocks of DNA. Prof Jeremy Farrar, director of the Wellcome Trust, said: "I can see a future where genetics is going to come into every bit of medicine from cardiology to oncology to infectious diseases." "Twenty years from now there's going to be a plethora of those, we will have a series of mutations which academics and industry will have developed therapies for, which will be targeted at you and specific for that cancer." He said chemotherapy, which attacks all dividing cells in the body, would be replaced with such therapies. "We will look back in 20 years' time and think of blockbuster chemotherapy [as] a thing of the past and we'll think 'Gosh, what an era that was'." David Cameron has announced a series of investments across government, industry and charities totalling £300m ($500m).
Velcroman1 (1667895) writes "Michael Ramsay and Jim Barton created a revolution with TiVo, a device that challenged the notion that we had to watch TV shows when they aired. And they hoped to do it again with Qplay, a device that challenged the notion that short-form videos had to be consumed one at a time, like snacks instead of meals. Qplay streamed curated queues of short-form Internet video to your TV using a small, simple box controlled by an iPad app. So what went wrong? Unlike TiVo, the Qplay box was difficult to justify owning, and thevalue of the service itself is questionable. And as of last week, Qplay is closed."
An anonymous reader writes with a bit of pith from TechDirt: Every so often, people who don't really understand the importance of anonymity or how it enables free speech (especially among marginalized people), think they have a brilliant idea: "just end real anonymity online." They don't seem to understand just how shortsighted such an idea is. It's one that stems from the privilege of being in power. And who knows that particular privilege better than members of the House of Lords in the UK — a group that is more or less defined by excess privilege? The Communications Committee of the House of Lords has now issued a report concerning "social media and criminal offenses" in which they basically recommend scrapping anonymity online.
New submitter Randall Booth writes Fotopedia has sent notice to its users that it is shutting down. 'We are sorry to announce that Fotopedia is shutting down. As of August 10, 2014, Fotopedia.com will close and our iOS applications will cease to function. Our community of passionate photographers, curators and storytellers has made this a wonderful journey, and we'd like to thank you for your hard work and your contributions. We truly believe in the concept of storytelling but don't think there is a suitable business in it yet. If you submitted photos and stories to Fotopedia, your data will be available to download until August 10, 2014. After this date, all photos and data will be permanently deleted from our servers."
First time accepted submitter wijnands (874114) writes Star Wars crews have started filming on the small Irish Island of Skellig Michael. This island, listed as a Unesco world heritage site, features the remains of a 6th century monastery as well as breeding populations of puffins, manx shearwaters, storm petrels, guillemots and kittiwakes. Currently the Irish navy has deployed one vessel to maintain a two-mile exclusion zone around the island. Unesco is now concerned about what is going on the island, which is only visited 13 times a year by tourist groups, and has asked the Irish government for an explanation.
New submitter BobandMax writes ExamSoft, the management platform software that handles digital bar exam submissions for multiple states, experienced a severe technical meltdown on Tuesday, leaving many graduates temporarily unable to complete the exams needed to practice law. The snafu also left bar associations from nearly 20 states with no choice but to extend their submission deadlines.
It's not the first time, either: a classmate of mine had to re-do a state bar exam after an ExamSoft glitch on the first go-'round. Besides handling the uploading of completed exam questions, ExamSoft locks down the computer on which it runs, so Wikipedia is not an option.
An anonymous reader writes: Amazon has waged a constant battle with publishers over the price of ebooks. They've now publicly laid out their argument and the business math behind it. "We've quantified the price elasticity of e-books from repeated measurements across many titles. For every copy an e-book would sell at $14.99, it would sell 1.74 copies if priced at $9.99. So, for example, if customers would buy 100,000 copies of a particular e-book at $14.99, then customers would buy 174,000 copies of that same e-book at $9.99. Total revenue at $14.99 would be $1,499,000. Total revenue at $9.99 is $1,738,000." They argue that capping most ebooks at $9.99 would be better for everyone, with the money split out 35% to the author, 35% to the publisher, and 30% to Amazon.
Author John Scalzi says Amazon's reasoning and assumptions are a bit suspect. He disagrees that "books are interchangeable units of entertainment, each equally as salable as the next, and that pricing is the only thing consumers react to." Scalzi also points out that Amazon asserts itself as the only revenue stream for authors, which is not remotely true. "Amazon's assumptions don't include, for example, that publishers and authors might have a legitimate reason for not wanting the gulf between eBook and physical hardcover pricing to be so large that brick and mortar retailers suffer, narrowing the number of venues into which books can sell. Killing off Amazon's competitors is good for Amazon; there's rather less of an argument that it's good for anyone else."
Apache is behind a huge percentage of the world's websites, and the Apache Software Foundation is the umbrella organization that provides licensing and stucture for open source projects ranging from the Apache Web server to Apache OpenOffice to small utilities that aren't household names but are often important to a surprising number of people and companies. Most of us never get to meet the people behind groups like the Apache Software Foundation -- except today we tag along with Tim Lord at OSCON and chat with Apache Software Foundation Executive Vice President Rich Bowen -- who is also Red Hat's OpenStack Community Liason. (Alternate Video Link) Update: 07/30 22:23 GMT by T : Note that Bowen formerly served as Slashdot sister site SourceForge's Community Manager, too.
rtoz sends this news from the BBC: The UK government has announced that driverless cars will be allowed on public roads starting in January next year. It also invited cities to compete to host one of three trials of the tech, which would start at the same time. In addition, ministers ordered a review of the UK's road regulations to provide appropriate guidelines. ... The debate now is whether to allow cars, like the prototype unveiled by Google in May, to abandon controls including a steering wheel and pedals and rely on the vehicle's computer. Or whether, instead, to allow the machine to drive, but insist a passenger be ready to wrest back control at a moment's notice.
Andreas Kolbe writes: The Daily Dot's EJ Dickson reports how she accidentally discovered that a hoax factoid she added over five years ago as a stoned sophomore to the Wikipedia article on "Amelia Bedelia, the protagonist of the eponymous children's book series about a 'literal-minded housekeeper' who misunderstands her employer's orders," had not just remained on Wikipedia all this time, but come to be cited by a Taiwanese English professor, in "innumerable blog posts and book reports", as well as a book on Jews and Jesus. It's a cautionary tale about the fundamental unreliability of Wikipedia. And as Wikipedia ages, more and more such stories are coming to light.
An anonymous reader writes: Earlier this year, just over half of the military officers put in charge of U.S. nuclear launch facilities were implicated in an exam cheating scandal. The Air Force conducted regular exams to keep officers current on the protocols and skills required to operate some of the world's most dangerous weapons. But the way they graded the test caused problems. Anything below a 90% score was a fail, but the remaining 10% often dictated how a launch officer's career progressed. There might not be much functional difference between a 93% and a 95%, but the person scoring higher will get promoted disproportionately quicker. This inspired a ring of officers to cheat in order to meet the unrealistic expectations of the Air Force. Now, in an effort to clean up that Missile Wing, the Air Force is making the exams pass/fail. The officers still need to score 90% or higher (since it's important work with severe consequences for failure), but scores won't be recorded and used to compete for promotions anymore. The Air Force is also making an effort to replace or refurbish the aging equipment that runs these facilities.
jrepin writes: Today, a child without access to a computer (and the Internet) at home is at a disadvantage before he or she ever sets foot in a classroom. The unfortunate reality is that in an age where computer skills are no longer optional, far too many families don't possess the resources to have a computer at home. Linux Journal recently had the opportunity to talk with Ken Starks about his organization, Reglue (Recycled Electronics and Gnu/Linux Used for Education) and its efforts to bridge this digital divide.
chicksdaddy writes: A four-year-old vulnerability in an open source component that is a critical part of Android leaves hundreds of millions of mobile devices susceptible to silent malware infections. The vulnerability affects devices running Android versions 2.1 to 4.4 ("KitKat"), according to a statement released by Bluebox. The vulnerability was found in a package installer in affected versions of Android. The installer doesn't attempt to determine the authenticity of certificate chains that are used to vouch for new digital identity certificates. In short, Bluebox writes, "an identity can claim to be issued by another identity, and the Android cryptographic code will not verify the claim."
The security implications of this are vast. Malicious actors could create a malicious mobile application with a digital identity certificate that claims to be issued by Adobe Systems. Once installed, vulnerable versions of Android will treat the application as if it was actually signed by Adobe and give it access to local resources, like the special webview plugin privilege, that can be used to sidestep security controls and virtual 'sandbox' environments that keep malicious programs from accessing sensitive data and other applications running on the Android device. The flaw appears to have been introduced to Android through an open source component, Apache Harmony. Google turned to Harmony as an alternative means of supporting Java in the absence of a deal with Oracle to license Java directly.
Work on Harmony was discontinued in November, 2011. However, Google has continued using native Android libraries that are based on Harmony code. The vulnerability concerning certificate validation in the package installer module persisted even as the two codebases diverged.
New submitter meeotch writes: According to a new study by the Urban Institute, 35% of U.S. adults with a credit history (91% of the adult population of the U.S.) have debt "in collections" — a status generally not acquired until payments are at least 180 days past due. Debt problems seem to be worse in the South, with states hovering in the 40%+ range, while the Northeast has it better, at less than 30%. The study's authors claim their findings actually underrepresent low-income consumers, because "adults without a credit file are more likely to be financially disadvantaged."
Oddly, only 5% of adults have debt 30-180 days past due. This latter fact is partially accounted for by the fact that a broader range of debt can enter "in collections" status than "past due" status (e.g. parking tickets)... But also perhaps demonstrates that as one falls far enough along the debt spiral, escape becomes impossible. Particularly in the case of high-interest debt such as credit cards — the issuers of which cluster in states such as South Dakota, following a 1978 Supreme Court ruling that found that states' usury laws did not apply to banks headquartered in other states.
Even taking into account the folks who lost a parking ticket under their passenger seat, 35% is a pretty shocking number. Anyone have other theories why this number is so much higher than the 5% of people who are just "late"? How about some napkin math on the debt spiral?
An anonymous reader writes: Wladimir Palant is the creator of the Adblock Plus browser extension, but he often gets asked how it compares to a similar extension for Chrome called Adblock. In the past, he's told people the two extensions achieve largely the same end, but in slightly different ways. However, recent changes to the Adblock project have him worried. "AdBlock covertly moved from an open development model towards hiding changes from its users. Users were neither informed about that decision nor the reasons behind it." He goes through the changelog and highlights some updates that call into question the integrity of Adblock. For example, from an update on June 6th: "Calling home functionality has been extended. It now sends user's locale in addition to the unique user ID, AdBlock version, operating system and whether Google Search ads are being allowed. Also, AdBlock will tell getadblock.com (or any other website if asked nicely) whether AdBlock has just been installed or has been used for a while — again, in addition to the unique user ID." Of course, Palant has skin in this game, and Adblock Plus has dealt with fallout from their "acceptable ads policy," but at least it's still developed in the open.
An anonymous reader writes: Today Senator Patrick Leahy (D-VT) introduced a bill that would ban bulk collection of telephone records and internet data for U.S. citizens. This is a stronger version of the legislation that passed the U.S. House in May, and it has support from the executive branch as well. "The bill, called the USA Freedom Act, would prohibit the government from collecting all information from a particular service provider or a broad geographic area, such as a city or area code, according to a release from Leahy's office. It would expand government and company reporting to the public and reform the Foreign Intelligence Surveillance Court, which reviews NSA intelligence activities. Both House and Senate measures would keep information out of NSA computers, but the Senate bill would impose stricter limits on how much data the spy agency could seek."
Qbertino (265505) writes I've been musing about a security setup to allow my coworkers/users access to files from the outside. I want security to be a little safer than pure key- or password-based SSH access, and some super-expensive RSA Token setup is out of question. I've been wondering whether there are any feasible and working FOSS and open hardware-based security token generator projects out there. It'd be best with ready-made server-side scripts/daemons. Perhaps something Arduino or Raspberry Pi based? Has anybody tried something like this? What are your experiences? What do you use? How would you attempt an open hardware FOSS solution to this problem?